Stricell - Stretch mark prevention & treatment cream with liposomed plant stem cells of Centella Asiatica. Improves the overall look of stretch marks. Reduces its color intensity. Improves the skin surface roughness.
Stretch Marks: Changes in the Appearance of the Skin
Many women (between 50% and 80% are reported) develop stretch marks during pregnancy. A number of creams have been claimed to remove these stretch marks once they have developed but there is no reliable evidence to support such claims. Stretch marks may be prevented in some women by daily massage but it is unclear if any particular ingredients bring special benefit. Stretch marks are common by the end of pregnancy, occurring in most women. Though they later shrink and fade somewhat, they do not go away. Any topical treatment which could prevent the development of striae would be welcomed by many women.
What are Stem Cells?
Stem cells are non-programmed and undifferentiated cells found in multi cellular organisms that have a large capacity of self-renewal. They are able to replenish themselves through mitotic division into two identical daughter cells and also have the unique ability to differentiate and become specialized cells with specific functions. The behaviour and characteristics of stem cells depends on the signals from the neighboring environment and epigenetic factors, which induce changes in gene expression. Their special properties provide stem cells with a great potential for regenerative medicine and cosmetic applications.
In vitro efficacy: effect of MEDITOPIC StriCell on the activity of epidermal stem cells. The effect of the product on the proliferative activity of the epidermal stem cells was studied by identification of stem cell markers Keratin 10 (expressed by all viable suprabasal keratinocytes in normal human epidermis, becoming a specific marker for differenciated keratinocytes) and Ki67 (marker of identity of pluripotency of epidermal stem cells).
Effect Of Meditopic Stricell In The Treatment Of Striae
In 1991, a double-blind test on 100 volunteers published in the International Journal of Cosmetic Science found that Centella Asiatic extract could prevent the development of stretch marks. In 2008, the Cochrane Collaboration performed a review of those tests, and came to the conclusion that the Centella Asiatic extract study was one of the only valid studies ever conducted on stretch mark prevention—and that Centella asiatica is the active ingredient responsible for the changes observed.